Participant Resources

Useful information for participants

What is the HEAL-COVID study?

COVID-19 is a disease caused by a virus called SARS-CoV-2, which affects not just the lungs but other organs like the heart, kidneys and blood vessels too.

Recently, we have become aware of people who have been unwell with COVID-19 developing new or worsened symptoms after being discharged from hospital – this is often called “Long COVID”. Long COVID is thought to represent a mix of conditions, and around 1 in 5 patients with COVID-19 develop symptoms currently associated with the term Long COVID. This is a serious group of conditions that can result in death and disability for some people.

We do not yet know which treatments are best to prevent and treat the increased death and disability occurring in some people with COVID after their discharge from hospital. There are several commonly used medicines that might help, but we do not know yet how well they work, or which treatments are the best. The HEAL-COVID study was set up to look at different treatments that work on the complications seen in patients who have been discharged from a hospital admission due to COVID-19.

Frequently Asked Questions

Why is this research being done?

COVID-19 is a disease caused by a virus called SARS-CoV-2, which affects not just the lungs but other organs like the heart, kidneys and blood vessels too. Recently, we have become aware of people who have been unwell with COVID-19 developing new or worsened symptoms after being discharged from hospital – this is often called “Long COVID”. Long COVID is thought to represent a mix of conditions and around 1 in 5 patients with COVID-19 develop symptoms currently associated with the term Long COVID.

Why have I been asked to take part?

You have been approached to take part in this study because you have been diagnosed with COVID-19 and are due to be discharged from hospital in the next few days.

What are the possible risks of taking part in the study?

There is potential that the treatment you are given as part of the study may improve your symptoms and help you recover from your COVID-19 illness more quickly. Though these medications are well-established treatments with a known profile of safety, like most medication, they also have potential side effects.

What happens if I change my mind?

You can contact us at any time if you wish to stop taking part in the study. You will still receive the standard care and the follow up usually offered by your hospital. With your permission, we would like to continue collecting information about your health from routine healthcare records.

What if new information becomes available?

Sometimes during the course of a research project, important new information becomes available about the treatments that are being studied. If this happens, your doctor or nurse will tell you about it and discuss with you whether you want to or should continue in the study. If the study is stopped for any other reason you will be told why and your continuing care will be arranged.

What happens if the study stops?

At the end of the study your treatment will return to standard care. If you are still experiencing symptoms your healthcare team will arrange appropriate ongoing care for you.

Will my taking part in the study be kept confidential?

Yes. The only people that have access to your data are those that need it for the conduct of the study. This includes the study doctors and nurses, the central trial team, Aparito (who provide the ATOM5 study app), inspectors or auditors on behalf of the Sponsor organisations and the regulatory authorities. With your permission, we will let your GP know that you are taking part in this research study.

Who is running the study?

Cambridge University Hospitals NHS Foundation Trust and The University of Cambridge jointly Sponsor this study and are responsible for managing it. They are based in United Kingdom. They have asked that the day to day running of the study is carried out by a team based at the Liverpool Clinical Trials Centre (LCTC, part of the University of Liverpool). The central trial team are researchers from the University of Cambridge, LCTC and Bangor University.

Will my information be shared for other research?

If you agree to take part in this study, you will have the option to allow future research at other organisations using your data collected as part of this study. These organisations may be universities, NHS organisations or companies involved in health and care research in this country or abroad. Your information will only be used by organisations and researchers to conduct research in accordance with the UK Policy Framework for Health. and Social Care Research, or equivalent standards.

What if there is problem?

Any complaint about the way you have been dealt with during the study or any possible harm you might suffer will be addressed. If you have a concern about any aspect of this study, you should ask to speak with one of your research team who will do their best to answer your questions.

Are there any financial costs or payments?

If you are asked to take Atorvastatin, you will be given repeat prescriptions for this by your GP, because the treatment lasts for longer than Apixaban. If you usually pay for your prescriptions, you will be exempt from paying for your trial treatment.

There will not be any other costs incurred to you by taking part in the HEAL-COVID study.

I have lost my medication, how do I request more?

Please contact your GP to request a new prescription.

I have been prescribed new medication can I take this alongside my trial medication?

Your GP has been informed of your participation in the trial. If you have been prescribed new medication and are unsure of whether this can be taken alongside your trial treatment, please contact your GP to discuss this.

I have lost or changed my phone and would like to continue completing questionnaires, what do I do?

If you have a new phone and wish to install the Atom5 app to continue completing follow-up surveys, please click here to register a new device.

If you are not able to re-install the Atom5 app and wish to continue to complete the questionnaires by telephone, please contact the central research team on

Where can I find out more information about Long COVID?

For advice about your COVID-19 recovery and more information about Long COVID, please visit our patient resources section.

Participant Resources

Thank you for taking part in HEAL-COVID. By being part of this, research study you are helping us to find out which treatments are best for patients like you, so that we can improve care for people with COVID-19 in the future.

We hope that you are recovering well after your hospital stay, but if you are concerned about any symptoms you are still experiencing, or would like to seek advice about managing your recovery at home, please have a look through the resources below.

Please note that the following are links to external websites, and the HEAL-COVID study is not responsible for their content.

Support & advice for my physical symptoms

For general information about what “Long COVID” is, and what symptoms might be associated with it visit:

For advice to help manage your symptoms at home and wellness tips to support your recovery visit:

If you have a specific concern about your healthcare, speak to your GP or contact NHS 111.

Support & advice about my mental health and wellbeing

For advice and support for grief and bereavement due to the COVID-19 pandemic, please visit:

For information about the types of mental health strains you might be experiencing during the pandemic, and advice about taking care of your mental health:

For tips to manage anxiety and stress during the pandemic:

For information and tips about supporting children through the pandemic:

For advice for families looking after someone with dementia during the COVID-19 pandemic:

For general advice about your mental wellbeing while staying at home:

Support & advice about my home, work or finances

To find out what support is available to you if you do not have a safe and stable home, have been made redundant, or are struggling to pay your bills visit:

For advice about your rights within the workplace during COVID-19:

For advice about claiming benefits:

If you are experiencing domestic abuse while staying at home due to the pandemic, information and support can be found at:

Help and Support

Setup a new device with the App

If you have a new mobile device and you need to setup the study App again then go here to get your new onboarding code.

Guide for re-installing the App

If you have a new mobile device and you need help in setting it up read this guide: Guide for setting up your new device.